Platelet-rich fibrin (PRF) is a second-generation blood concentrate, derived from human peripheral blood, capable of stimulating tissue regeneration. A solid and liquid PRF-based matrix can be obtained by centrifugation in accordance with specific centrifugation protocols such as Low Speed Centrifugation Protocol, without the addition of anticoagulants or external chemicals. It contains a greater number of leukocytes, growth factors and stem cells compared with PRP.
In periodontology and oral surgery, PRF-based matrices are used in order to promote soft and hard tissue healing. The wound healing benefits of platelet-rich fibrin preparations together with the low risk profile and disposability of a simple preparation procedure should encourage more clinicians to incorporate PRF as a treatment option in their practice to accelerate healing, reduce adverse events, and improve patient outcomes.
Lately many dentists are using PRF liquid combined with xenografts (porcine origin) for sticky bone preparation in multiple bone augmentation techniques. This combination seems to give us the opportunity to insert the implants in a shorter period of time achieving a good quality bone.
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